Inflammatory adaptive immunity in gliomas: roles of Toll-like receptors and chemokines
10.3760/cma.j.cn115354-20201029-00857
- VernacularTitle:胶质瘤炎性适应免疫：Toll样受体与趋化因子的作用
- Author:
Xiangtong XIE
1
;
Ke YAN
;
Xifeng FEI
;
Xuan MENG
;
Wenyu ZHU
;
Zhimin WANG
;
Qiang HUANG
Author Information
1. 上海交通大学医学院苏州九龙医院神经外科，苏州 215021
- Keywords:
Toll-like receptor;
Chemokine;
Bioinformatics;
Adaptive immunity
- From:
Chinese Journal of Neuromedicine
2021;20(12):1264-1269
- CountryChina
- Language:Chinese
-
Abstract:
The research on relation between cancer and adaptive immunity is developing in depth. One of its signs is to optimize the key molecules and their pathways for regulating adaptive immunity through high-throughput molecular bioinformatics analysis. Based on the fact that cancer is an uncontrolled inflammation, adaptive immune-related cells are the main members driving the development of controllable inflammation to non-controllable inflammation, and the research on its molecular regulatory mechanism is a hot topic nowadays. Based on the in-depth sequencing database and bioinformatics analysis of the non-controllable growth (malignant transformation) of these adaptive immune-related cells, the research progress of Toll-like receptors and chemokines is summarized as follows.
