Relationship between ascorbic acid and depression
10.3760/cma.j.cn115354-20210526-00339
- VernacularTitle:抗坏血酸与抑郁症的关系
- Author:
Fang HUANG
1
;
Hong YUE
;
Aimei WU
;
Yurong TIAN
;
Kangrui ZHANG
;
Zhenxiong YULIU
;
Ruorui YANG
;
Juncang WU
Author Information
1. 皖南医学院研究生学院，芜湖 241002
- Keywords:
Ascorbic acid;
Depression;
Mechanism
- From:
Chinese Journal of Neuromedicine
2021;20(11):1182-1187
- CountryChina
- Language:Chinese
-
Abstract:
Depression is a common emotional disorder, which has high incidence rate and mortality worldwide. Ascorbic acid (AA) is also known as vitamin C. As a kind of reducing vitamin, AA participates in anti-oxidation, enzyme assistance and neuro-modulation in the central nervous system. Clinical evidence and animal studies show that AA has anti-depressant effect. This article reviews the function of AA in the nervous system, the current researches on relation between AA and depression, and possible mechanism, and analyzes its therapeutic significance in this disease, hoping to provide new ideas for the clinical treatment of depression.
