Evaluation of Corneal Biomechanical Properties Following Penetrating Keratoplasty Using the Ocular Response Analyzer.
10.3341/kjo.2010.24.3.139
- Author:
Joo Young SHIN
1
;
Jin Seok CHOI
;
Joo Youn OH
;
Mee Kum KIM
;
Jin Hak LEE
;
Won Ryang WEE
Author Information
1. Department of Ophthalmology, Seoul National University Hospital, Seoul, Korea. wrwee@snu.ac.kr
- Publication Type:Original Article ; Comparative Study
- Keywords:
Cornea;
Intraocular pressure;
Penetrating keratoplasty
- MeSH:
Adolescent;
Adult;
Aged;
Cornea/*physiopathology;
*Diagnostic Techniques, Ophthalmological;
Elasticity;
Female;
Humans;
Intraocular Pressure;
*Keratoplasty, Penetrating;
Male;
Middle Aged;
Postoperative Period;
Young Adult
- From:Korean Journal of Ophthalmology
2010;24(3):139-142
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: To evaluate corneal biomechanical properties in eyes that had previously undergone penetrating keratoplasty (PK) using the ocular response analyzer (ORA). METHODS: We recruited 26 patients who had received unilateral PK. Corneal hysteresis (CH), corneal resistance factor (CRF), Goldmann-correlated intraocular pressure (IOPg), and cornea-compensated intraocular pressure (IOPcc) were measured with the ORA and were compared to the measurements from the contralateral eyes that did not undergo PK. RESULTS: The CH was 8.95+/-2.59 mmHg in eyes that underwent PK and 9.78+/-1.45 mmHg in the contralateral eyes that did not undergo PK (p=0.077). The CRF was 10.26+/-2.64 mmHg in post-PK eyes and 9.75+/-1.45 mmHg in the contralateral eyes (p=0.509), and the CH-CRF was significantly smaller in post-PK eyes (-1.31+/-2.32 mmHg in post-PK eyes vs. 0.03+/-0.88 mmHg in fellow eyes, p=0.016). The IOPg and IOPcc were significantly higher in the PK group than they were in the control group. The IOPcc's were 20.81+/-7.81 mmHg and 16.27+/-2.49 mmHg in post-PK and control eyes, respectively (p=0.011); and the IOPg's were 19.22+/-7.34 mmHg and 15.07+/-3.03 mmHg in post-PK and control eyes, respectively (p=0.019). The IOPcc-g's were 1.59+/-2.81 mmHg and 1.21+/-1.30 mmHg in post-PK and control eyes, respectively (p=0.412), and the central corneal thickness (CCT)'s were 489.11+/-90.60 microm and 556.24+/-42.84 microm in post-PK and control eyes, respectively (p=0.068). CONCLUSIONS: Following PK, CH tended to decrease while CRF tended to increase, significantly decreasing CH-CRF. A significantly higher intraocular pressure and a thinner CCT following PK may have contributed to the observed changes in these corneal biomechanical parameters.
