Recent advance in cerebrospinal fluid biomarkers in patients with anti- N-methyl- D-aspartic acid receptor encephalitis
10.3760/cma.j.cn115354-20200924-00763
- VernacularTitle:抗NMDA受体脑炎患者脑脊液生物标志物的研究进展
- Author:
Keyu YANG
1
;
Zan DONG
;
Yuchen LI
;
Jing WANG
;
Rui WANG
;
Jie WANG
Author Information
1. 山西医科大学第一临床医学院，太原 030000
- Keywords:
Anti-N-methyl-D-aspartic acid receptor encephalitis;
Biological factor;
Biomarker;
Cerebrospinal fluid
- From:
Chinese Journal of Neuromedicine
2021;20(6):640-643
- CountryChina
- Language:Chinese
-
Abstract:
Anti- N-methyl- D-aspartic acid (NMDA) receptor encephalitis is an autoimmune encephalitis. Most patients have a good prognosis, but a small number of patients have memory impairment and other sequelaes. Early immunotherapy is a key factor for good prognosis of patients with this disease. However, a key problem in the treatment of this disease is the lack of biomarkers for disease monitoring and prognosis assessment. Therefore, it is positive for guiding the diagnosis and treatment and evaluating the prognosis to find biomarkers that can reflect the disease. Here, biological factors abnormally elevated in cerebrospinal fluid of patients with anti-NMDA receptor encephalitis are reviewed, and biological factors with potential as biomarkers are summarized.
