Recent advance in relation between transient receptor potential vanilloid-1 receptor and cognitive dysfunction
10.3760/cma.j.cn115354-20200227-00125
- VernacularTitle:TRPV1受体与认知障碍相关性的研究进展
- Author:
Jie YUAN
1
;
Kaiqi SU
;
Ruiqing LI
;
Huanhuan LIU
;
Huili FENG
;
Di HUANG
;
Xiaodong FENG
Author Information
1. 河南中医药大学康复医学院，郑州 450046
- Keywords:
Transient receptor potential vanilloid-1;
Cognitive dysfunction;
Alzheimer's disease;
Parkinson's disease;
Stroke
- From:
Chinese Journal of Neuromedicine
2021;20(3):308-312
- CountryChina
- Language:Chinese
-
Abstract:
The correlation between transient receptor potential vanilloid-1 (TRPV1) receptor and peripheral nervous system diseases has been confirmed. In recent years, studies have shown that TRPV1 plays an important role in the central nervous system; its wide distribution in the hippocampus, cortex, and midbrain bridges the correlation between TRPV1 receptor and cognitive learning and memorial function. This paper reviews the biological role of TRPV1 receptor in the nervous system at home and abroad and concludes the relations of TRPV1 receptor with cognitive associated diseases, aiming at providing theory basis for whether TRPV1 receptors can be used as therapeutic drug targets for cognitive associated diseases.
