Interventional therapy with balloon predilation of different diameters in carotid artery stenosis: a comparative study
10.3760/cma.j.cn115354-20200621-00498
- VernacularTitle:不同直径球囊预扩张介入治疗颈动脉狭窄的对比研究
- Author:
Ruiqing CHEN
1
;
Chen CHEN
;
Zengpin LIU
Author Information
1. 河北医科大学第二医院神经内科，石家庄 050000
- Keywords:
Carotid artery stenosis;
Carotid artery stenting;
Balloon predilation;
Complication
- From:
Chinese Journal of Neuromedicine
2021;20(2):165-169
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the safety and efficacy of interventional therapy with balloon predilation of different diameters in severe carotid artery stenosis.Methods:One hundred patients with symptomatic severe carotid artery stenosis admitted to our hospital from January 2018 to September 2018 were selected. These patients were randomly divided into 4 mm balloon predilation group and 5 mm balloon predilation group ( n=50). The surgical success rate, residual stenosis rate, changes of heart rate and blood pressure before and after surgery, and complications were compared between the two groups. Results:The success rate of surgery in both groups was 100%. The average preoperative vascular stenosis rate in the 4 mm balloon predilation group was (84.8±8.6)%, and postoperative residual stenosis rate was (12.2±6.2)%, with significant difference ( P<0.05); in the 5 mm balloon predilation group, the average preoperative vascular stenosis rate was (82.1±8.0)%, and the postoperative residual stenosis rate was (6.4±6.1)%, with significant difference ( P<0.05). The postoperative residual stenosis rate of the 5 mm balloon predilation group was significantly lower than that of the 4 mm balloon predilation group ( P<0.05). In the 4 mm balloon predilation group, systolic blood pressure decreased by (19.8±22.3) mmHg and heart rate decreased by (11.0±9.7) times/min; the systolic blood pressure decreased by (14.0±28.5) mmHg and heart rate decreased by (7.0±10.8) times/min in the 5 mm balloon predilation group; no significant differences were noted between the two groups in blood pressure and heart rate ( P>0.05). Complications was noted in 28 patients from the 4 mm balloon predilation group and 25 patients from the 5 mm balloon predilation group, without statistical difference ( P>0.05). Conclusion:The application of the two kinds of diameter balloon in the interventional treatment of severe carotid artery stenosis is safe and effective, and the short-term improvement efficay of 5 mm balloon predilation is better than that of 4 mm balloon predilation.
