Recent advance in role of exosomes in gliomas

VernacularTitle:外泌体与胶质瘤的关系研究进展
Author: Menglan ZHANG ¹ ; Yujing TAN ; Rentao HOU ; Libo LI
Author Information

1. 南方医科大学中西医结合医院消化道肿瘤内科，广州　510000
Keywords: Glioma; Exosomes; Micro RNA
From: Chinese Journal of Neuromedicine 2021;20(1):103-106
CountryChina
Language:Chinese
Abstract: Gliomas are the most common primary intracranial tumors, which have genetic heterogeneity. It is impossible to accurately evaluate the dynamic evolution of tumor genes and microenvironment only by pathological examination after surgery. As one of the smallest extracellular vesicles secreted by cells, exosomes can be used as potential biomarkers and carriers of intercellular information transmission. It can promote glioma cell proliferation, immune escape and chemoradiotherapy resistance, improve blood oxygen microenvironment, and enhance the ability of invasion and metastasis. The relations of exosomes with glioma occurrence and development are summarized as follows.