Diagnostic value of 18F-fulorodeoxyglucose marked positron emission computed tomography in anti- N-methyl-daspartate receptor encephalitis and viral encephalitis
10.3760/cma.j.cn115354-20200802-00622
- VernacularTitle:18F-FDG PETCT在抗NMDA受体脑炎及病毒性脑炎诊断中的价值
- Author:
Zan DONG
1
;
Keyu YANG
;
Jing WANG
;
Rui WANG
;
Yuchen LI
;
Jie WANG
Author Information
1. 山西医科大学研究生院，太原 030000
- Keywords:
Encephalitis;
Anti- N-methyl-Daspartate receptor encephalitis;
Viral encephalitis;
Positron emission computed tomography;
Cerebral metabolic
- From:
Chinese Journal of Neuromedicine
2021;20(1):87-91
- CountryChina
- Language:Chinese
-
Abstract:
The clinical manifestations of anti- N-methyl-daspartate (NMDA) receptor encephalitis and viral encephalitis are similar but the treatments and prognoses are different, so the early differentiation of the two diseases is very important. Early diagnosis is affected by delayed antibody detection and false negative detection, while routine auxiliary tests lack specificity; therefore, they have limited value in identification. The 18F-fulorodeoxyglucose (FDG) marked positron emission computed tomography (PETCT) is highly sensitive to abnormal cerebral metabolism in the early stage of anti-NMDA receptor encephalitis, showing a characteristic metabolic pattern of frontal or temporal lobe increase metabolism and occipital decrease metabolism. The number of patients who underwent 18F FDG PETCT examination for viral encephalitis was small; different kinds of viral encephalitis show different brain metabolism, but there was no characteristic hypometabolism of the occipital lobe. This paper reviews the cerebral metabolic characteristics of 18F-FDG PETCT in anti-NMDA receptor encephalitis and viral encephalitis.
