Recent advance in pathophysiological mechanism of micro RNAs regulating autophagy in ischemic stroke

VernacularTitle:miRNAs调控自噬在缺血性脑卒中病理生理机制中的研究进展
Author: Maodong WU ¹ ; Qinglun SU ; Zhen LIU ; Haimin DU ; Jing LU ; Zhenjie SUN
Author Information

1. 南京医科大学康达学院附属连云港市第一人民医院康复科　222000
Keywords: Ischemic stroke; Micro RNAs; Autophagy
From: Chinese Journal of Neuromedicine 2020;19(12):1277-1282
CountryChina
Language:Chinese
Abstract: Micro RNAs are a kind of conserved short non-coding RNAs that regulate life activities at molecular level. Micro RNAs are active in various stages of autophagy after ischemic stroke; micro RNAs play protective or destructive roles in autophagy after stroke. Based on the autophagy process, we discuss the possible mechanism of autophagy regulated by micro RNAs through autophagy related genes or pathways, and analyze the application prospect of micro RNAs in stroke diagnosis and treatment.