Recent advance in cognitive impairment caused by white matter hyperintensity based on diffusion tensor imaging
10.3760/cma.j.cn115354-20200731-00617
- VernacularTitle:基于弥散张量成像的脑白质高信号认知障碍的研究进展
- Author:
Hui MA
1
;
Luqing ZHAO
;
Wenmin YIN
Author Information
1. 山西医科大学附属人民医院神经内科，太原 030012
- Keywords:
White matter hyperintensity of presumed vascular origin;
Cognitive impairment;
Diffusion tensor imaging;
White matter microstructure;
Brain structural net
- From:
Chinese Journal of Neuromedicine
2020;19(10):1071-1074
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, many studies have found that white matter hyperintensity (WMH) of presumed vascular origin is closely related to cognitive impairment, which reflects the negative effects of white matter macrostructure damage on cognition, while diffusion tensor imaging (DTI) can quantify white matter microstructure damage through different imaging parameters. A variety of DTI parameters are associated with cognitive impairment in WMH, and are of great value in early diagnosis, evaluation of progress risk and efficacy of cognitive impairment. On the basis of DTI, the relevant parameters of brain structural network obtained by joint the graph theory analysis method are also considered to be related to the cognitive impairment with WMH. This paper reviews the latest progress of DTI derived parameters, brain structural network parameters and their relations with WMH cognitive impairment.
