Influencing factors for intracranial hemorrhage in patients with acute large vessel occlusion stroke of anterior circulation after endovascular mechanical thrombectomy
10.3760/cma.j.cn115354-20200107-00015
- VernacularTitle:急性前循环大血管闭塞性脑卒中机械取栓术后颅内出血的影响因素分析
- Author:
Haibing REN
1
;
Jing YAN
;
Xiaohui ZHAO
;
Tingting XING
;
Jianying ZHANG
;
Guodong XIAO
;
Yongjun CAO
Author Information
1. 上海市浦东新区人民医院神经内科 201299
- Keywords:
Ischemic stroke;
Large artery occlusion in anterior circulation;
Mechanical thrombectomy;
Intracranial hemorrhage;
Influencing factor
- From:
Chinese Journal of Neuromedicine
2020;19(9):890-896
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the influencing factors for intracranial hemorrhage (ICH) in patients with acute large vessel occlusion stroke (ALVOS) of anterior circulation after mechanical thrombectomy (MT).Methods:From October 2015 to March 2018, the clinical data of 116 patients with ALVOS of anterior circulation accepted MT were analyzed retrospectively in our hospitals. These patients were divided into ICH group ( n=31) and non-ICH group ( n=85) according to whether there was ICH after operation. Univariate and multivariate Logistic regression models were used to analyze the independent influencing factors for ICH after MT. Results:Univariate analysis showed that there were significant differences in preoperative Alberta Stroke Program Early CT (ASPECT) scores, baseline systolic pressure, and preoperative blood glucose level between ICH group and non-ICH group ( P<0.05). Multivariate analysis showed that after adjusting baseline Glasgow coma scale scores, preoperative ASPECT scores ( OR=0.770, 95%CI: 0.610-0.0.971, P=0.027), baseline systolic pressure ( OR=1.029, 95%CI: 1.005-1.054, P=0.017), preoperative blood glucose level ( OR=1.177, 95%CI: 1.010-1.372, P=0.036) were independent influencing factors for ICH. Conclusion:The patients with low preoperative ASPECT scores, high baseline systolic pressure, and high blood glucose are prone to have ICH after MT in patients with ALVOS of anterior circulation.
