Flow diversion combined with coil embolization in treatment of intracranial aneurysms: an efficacy analysis
10.3760/cma.j.cn115354-20200212-00073
- VernacularTitle:血流导向装置联合弹簧圈栓塞治疗颅内动脉瘤的效果分析
- Author:
Haowen XU
1
;
Kaihao HAN
;
Xiaojie FU
;
Yongjie YUAN
;
Zibo WANG
;
Baojun YAN
;
Tao QUAN
;
Sheng GUAN
Author Information
1. 郑州大学第一附属医院神经介入科，郑州 450052
- Keywords:
Intracranial aneurysm;
Flow diversion;
Coil;
Prognosis
- From:
Chinese Journal of Neuromedicine
2020;19(8):799-804
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the efficacy of flow diversion combined with coil embolization in treatment of intracranial aneurysms.Methods:The clinical data of 110 patients with intracranial aneurysms treated by flow diversion in our hospital from April 2015 to September 2019 were retrospectively analyzed. In these patients, 48 were treated by flow diversion combined with coil embolization and 62 were treated by flow diversion alone; the efficacy and safety of patients from the two groups were compared.Results:Blood flow diversion was successfully implanted into all 110 patients, with technical success rate of 100%. Immediate complete occlusion rate in the flow diversion combined with coil embolization group (16.7%) was significantly higher than that in the flow diversion group (1.6%, P<0.05). There was no significant difference in the incidence of perioperative complications between flow diversion combined with coil embolization group and flow diversion group (4.17% vs. 4.84%, P>0.05). During the mean follow-up of 6.72±3.80 months, modified Rankin scale (mRS) scores of patients in the flow diversion combined with coil embolization group were all 0; one patient had mRS score of 1, one patients had mRS scores of 2, and 60 patients had mRS score of 0 in patients from the flow diversion group; no significant difference was noted between the two groups ( P>0.05). Patients in the flow diversion combined with coil embolization group had significantly higher rate of complete aneurysm occlusion than those in the flow diversion group (88.3% vs. 66.1%, P<0.05). Conclusions:Flow diversion is an effective and safe strategy in treatment of intracranial aneurysms. Flow diversion combined with coil embolization can effectively promote early healing of aneurysms in selective patients.
