MR imaging study of arachnoid granulation in patients with cerebral venous sinus thrombosis
10.3760/cma.j.cn115354-20200115-00041
- VernacularTitle:颅内静脉窦血栓形成患者蛛网膜颗粒的MRI研究
- Author:
Kelei LI
1
;
Liangfeng WEI
;
Jiaxing WANG
;
Yacao FAN
;
Jianwu WU
;
Jun LI
;
Liang XIAN
;
Shousen WANG
Author Information
1. 解放军联勤保障部队第九〇〇医院神经外科，福州 350025
- Keywords:
Cerebral venous sinus thrombosis;
Arachnoid granulation;
Contrast-enhanced MR venography;
Differential diagnosis
- From:
Chinese Journal of Neuromedicine
2020;19(8):770-774
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the changes and imaging features of arachnoid granulation (AG) in patients with cerebral venous sinus thrombosis (CVST).Methods:The clinical and imaging data of 35 patients with idiopathic CVST confirmed by MR imaging combined with CE-MRV or DSA in our hospital from January 2013 to December 2018, and 35 healthy controls collected at the physical examination center at the same time period were detected. The sizes and numbers of AG were compared between the two groups, and the MR imaging features of CVST and AG in patients with CVST at different courses were compared.Results:(1) In 35 patients with CVST, AG was found in 14 patients, and the average diameter was (5.19±2.40) mm, ranged from 1.83-11.77 mm; in the control group, AG was found in 23 patients, and the average diameter was (4.45±2.03) mm, ranged from 1.45-9.87 mm; no statistical difference was noted in diameter between the two groups ( t=2.121, P=0.221), and the number of AG showed statistical difference between the two groups (χ 2=4.644, P=0.031). (2) In 8 patients with CVST at acute phase, CVST showed hypointense on T2WI and FLAIR; in 20 patients with CVST at subacute phase, CVST showed hyperintense on T2WI and FLAIR; in 7 patients with CVST at chronic phase, CVST showed hyperintense on T2WI and FLAIR. At any stage of venous sinus thrombosis, AG showed high signal on T2WI and low signal on FLAIR. Conclusion:AG detection rate in CVST patients is lower than that in normal controls; MR imaging T2WI and FLAIR sequences could effectively distinguish CVST with AG.
