Safety and efficacy of mechanical thrombectomy in minor stroke with large vessel occlusion
10.3760/cma.j.cn115354-20200430-00323-1
- VernacularTitle:血管内机械取栓治疗大血管闭塞性轻型脑卒中的安全性和有效性分析
- Author:
Guifang WANG
1
;
Xiaoqian YANG
;
Yilei XIAO
;
Weibin MA
;
Shuping LIU
;
Zuneng LU
Author Information
1. 聊城市人民医院神经内科 252000
- Keywords:
Minor stroke;
Large vessel occlusion;
Mechanical thrombectomy
- From:
Chinese Journal of Neuromedicine
2020;19(7):711-714
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the efficacy and safety of mechanical thrombectomy (MT) in patients with minor stroke with large vessel occlusion (LVO).Methods:Twenty-three patients with minor stroke with LVO, admitted to our hospital from January 2017 to July 2019, were consecutively collected in our study; patients with contraindications of intravenous thrombolysis should be treated with direct thrombectomy, and the left were given bridging therapy (intravenous thrombolysis combined with MT). NIHSS scores were used to assess the degrees of neurological impairment at admission, and 12 h and 7 d after treatment. Vascular recanalization was assessed by modified cerebral infarction thrombolysis (mTICI) grading, with grading 2B-3 defined as successful recanalization. The prognoses 90 d after treatment were assessed by modified Rankin scale (mRS), and mRS scores≤2 was classified as having good prognosis. Safety indicators included symptomatic intracranial hemorrhage, incidence of complications, and mortality 90 d after treatment.Results:Twenty-two patients had successfully recanalization; 19 patients had mTICI grading 3 and 3 patients had grading 2B. The NIHSS scores were 3 (2, 5) at admission, 2 (2, 3) 12 h after treatment, and 2 (1, 2) 7 d after treatment, with significant difference ( χ2=14.028, P=0.001); NIHSS scores 12 h and 7 d after treatment were significantly lower than those at admission ( P<0.05). Sixteen patients (69.6%) enjoyed good prognosis and 7 patients (30.4%) had poor prognosis. In terms of safety, two patients had symptomatic intracranial hemorrhage,10 had systemic complications, and one died during 90-d of follow-up. Conclusion:MT is effective and safe in minor stroke patients with LVO.
