Recent advances in treatment status and molecular biology of eosinophilic pituitary adenomas
10.3760/cma.j.cn115354-20191220-00763
- VernacularTitle:嗜酸性谱系垂体腺瘤的治疗现状及分子生物学研究进展
- Author:
Yuming WANG
1
;
Xiaoling YAN
;
Xuebin ZHANG
;
Xin GAO
;
Ying HUANG
Author Information
1. 天津医科大学研究生院,天津 300070
- Keywords:
Eosinophilic lineage;
Pituitary adenoma;
Molecular biology;
Treatment
- From:
Chinese Journal of Neuromedicine
2020;19(3):241-246
- CountryChina
- Language:Chinese
-
Abstract:
After the publication of pituitary adenoma classification (2017) by WHO, a more detailed classification of pituitary adenomas is performed. This review focuses on the related treatment methods and deficiencies of current new classification of eosinophilic lineage pituitary adenomas, such as growth hormone cell adenoma, prolactin cell adenoma, and thyroid stimulating hormone cell adenoma. Through the analysis and research of gene mutations, gene transcriptional changes and epigenetics, we hope to search for potential therapeutic targets from the perspective of molecular biology to find new therapeutic methods.