Recent advance in mesenchymal stem cell-derived exosomes in treatment of central nervous system diseases
10.3760/cma.j.issn.1671-8925.2020.02.018
- VernacularTitle:间充质干细胞来源外泌体治疗中枢神经系统疾病的研究进展
- Author:
Yesheng SUN
1
;
Zhiqian YANG
;
Wei ZHANG
Author Information
1. 广东药科大学附属第一医院神经外科
- Keywords:
Mesenchymal stem cell;
Exosome;
Central nervous system disease
- From:
Chinese Journal of Neuromedicine
2020;19(2):202-207
- CountryChina
- Language:Chinese
-
Abstract:
The treatment of central nervous system diseases has always been a hot topic,owning to its complexity and existence of blood-brain barrier.In recent years,studies on mesenchymal stem cells-derived exosomes (MSCs-EVS) showed that MSCs-EVS are not only potential therapeutic drugs for central nervous system diseases,but also natural carriers of therapeutic drugs due to their good biocompatibility and ability to cross the blood-brain barrier.This paper reviews the application and underling mechanism of MSCs-EVS in treatment of central nervous system diseases,and looks forward to its applications in central nervous system disease.
