Recent advance in clinical manifestations and differential diagnoses of Kikuchi-Fujimoto disease involving nervous system
10.3760/cma.j.issn.1671-8925.2020.01.016
- VernacularTitle:组织细胞坏死性淋巴结炎累及神经系统的临床表现及鉴别诊断的研究进展
- Author:
Jialei YANG
1
;
Lei WANG
;
Hualei CHEN
;
Fang XU
;
Shimin YIN
Author Information
1. 解放军火箭军特色医学中心
- Keywords:
Histiocytic necrotic lymphadenitis;
Kikuchi-Fujimoto disease;
Nervous system;
Clinical manifestation;
Differential diagnosis
- From:
Chinese Journal of Neuromedicine
2020;19(1):79-83
- CountryChina
- Language:Chinese
-
Abstract:
Histiocytic necrotic lymphadenitis is known as Kikuchi-Fujimoto disease (KFD).KFD is a systemic disease,which is characterized by fever,necrotizing lymphadenopathy and leukopenia.However,involvement of the central and peripheral nervous system is rare.It can present as aseptic meningitis,encephalomyelitis,peripheral neuropathy,cerebellar ataxia and tremor,which makes it difficult to be differentiated with other nervous system diseases.Our review summarizes the clinical manifestations and differential diagnoses of KFD involving nervous system in order to reduce misdiagnoses and mistreatments.
