Recent advance in endoplasmic reticulum stress -mediated inflammatory response after intracerebral hemorrhage
10.3760/cma.j.issn.1671-8925.2015.11.017
- VernacularTitle:脑出血后内质网应激介导炎症反应的研究现状
- Author:
Xuheng JIANG
1
;
Hongfei GE
;
Yu NI
;
Ji ZHANG
;
Xiaojun ZHANG
;
Hua FENG
;
Anyong YU
Author Information
1. 遵义医科大学附属医院急诊科
- Keywords:
Intracerebral hemorrhage;
Inflammatory response;
Endoplasmic reticulum stress;
Unfolded protein response
- From:
Chinese Journal of Neuromedicine
2019;18(11):1164-1167
- CountryChina
- Language:Chinese
-
Abstract:
Endoplasmic reticulum (ER) stress is an important mediator causing inflammatory response, which additionally exerts secondary injury after intracerebral hemorrhage (ICH) to influence brain function recovery through a variety of cell signaling and response, to regulate neural cells survival or death. Therefore, further understanding about the relation between ER stress and inflammatory response as well as the signal transduction pathway can provide new therapeutic strategies and evidence for treatment of ICH. The present review summarizes the process of ER stress activation and the relation between inflammatory response and ER stress activation after ICH.
