Clinical characteristics of three patients with restless leg syndrome mainly characterized by abdominal symptoms
10.3760/cma.j.issn.1671-8925.2019.10.011
- VernacularTitle:三例以腹部症状为主的不安腿综合征患者临床特点分析
- Author:
Junhua MEI
1
;
Xue GONG
;
Minzhen LIU
;
Guohua CHEN
;
Wei SHAO
;
Lijuan LI
;
Bingling ZHOU
;
Jinmei XU
;
Yulan GOU
Author Information
1. 武汉市第一医院神经内科睡眠医学中心 430022
- Keywords:
Restless leg syndrome;
Polysomnography;
Periodic leg movement
- From:
Chinese Journal of Neuromedicine
2019;18(10):1031-1034
- CountryChina
- Language:Chinese
-
Abstract:
Objective To summarize and analyze the clinical features and diagnosis and treatment methods of patients with restless leg syndrome (RLS) mainly characterized by abdominal symptoms, and provide the basis for improving the correct diagnosis and treatment rate of RLS. MethodsThree patients, admitted to and completed routine laboratory examination (blood analysis, blood biochemistry, serum iron, serum ferritin, etc.), imaging, electroencephalogram, and electromyography in our hospital from August 2018 to April 2019, were chosen in our study. Polysomnography monitor was used to record the patient's sleep process for 12 h. Sleep and psychological status were evaluated by Pittsburgh Sleep Quality Index (PSQI), RLS Self-rating Depression Scale (IRLS), Epworth Sleeping Scale (ESS), RLS-quality of life (RLS-QoL), Hamilton Anxiety Scale (HAMA) and Hamilton Depression Scale (HAMD).Results General examination, physical examination of nervous system, imaging, electroencephalogram, electromyography and routine biochemical examination showed no obvious abnormalities in the three patients. Serum iron decreased in two patients. Polysomnography results indicated that the sleep efficiency of the three patients was obviously decreased, the sleep latency was prolonged, the time of awakening during sleep and the times of awakenings were increased; and the sleep structure was disordered; rapid eye movement sleep was significantly reduced. Meanwhile, all three patients had moderate and severe PLM events. Excessive sleepiness in the daytime was noted; the quality of life was affected about one month, and the severity was severe; all three patients had severe anxiety without evident depression. The condition of three patients with pramipexole hydrochloric acid after treatment were significantly improved.Conclusion s RLS subtype with abdominal symptoms as chief complaint is relatively rare in clinical practice. If patients have abdominal pain and discomfort during sleep at night and can exclude organic diseases of the digestive system, the possibility of RLS should be considered. A good therapeutic effect can be obtained by using dopa receptor agonist such as pramipexole.
