Clinical efficacy observation and reconsideration of spontaneous hypertension pontine hemorrhage via microsurgery
10.3760/cma.j.issn.1671-8925.2019.10.005
- VernacularTitle:自发性脑桥出血微侵袭手术的疗效观察与再思考
- Author:
Shangming ZHANG
1
;
Mingchao SHANG
;
Lin ZHAO
;
Liangfeng WEI
;
Bangqing YUAN
;
Shousen WANG
Author Information
1. 解放军联勤保障部队第九〇〇医院神经外科
- Keywords:
Spontaneous pontine hemorrhage;
Puncture drainage and urokinase thrombolysis;
Craniotomy evacuation of hematoma
- From:
Chinese Journal of Neuromedicine
2019;18(10):996-1000
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the efficacy and experience of surgical approaches of puncture drainage and urokinase thrombolysis for spontaneous hypertensive pontine hemorrhage.Methods The clinical data of 42 patients with spontaneous pontine hemorrhage, admitted to our hospital from January 2014 to December 2018, were retrospectively analyzed. Craniotomy evacuation of hematoma was performed in 18 patients (control group), and puncture drainage and urokinase thrombolysis assisted by neuronavigation was performed in 24 patients (observation group). The clinical efficacies of the two groups were observed and analyzed.Results There were 24 patients having hematoma clearance rate≥50％, including 7 from control group and 17 from observation group. The hematoma clearance rate≥50％ in the observation group (70.83％) was significantly higher than that in the control group (38.89％,P<0.05). Postoperative Glasgow-Pittsburgh scale scores of the observation group (24.21±4.85) were slightly higher than those of the control group (23.61±5.45), and the mortality of the observation group (66.67％) was lower than that of the control group (72.22％) without statistical significance (P> 0.05).Conclusion The surgical approach of puncture drainage and urokinase thrombolysis can effectively improve hematoma clearance rate for spontaneous hypertensive pontine hemorrhage, but clinical prognoses are not improved due to influence of multiple factors.
