Recent advance in spinal bifida related genes
10.3760/cma.j.issn.1671-8925.2019.06.016
- VernacularTitle:脊柱裂相关基因的研究进展
- Author:
Yu LIU
1
;
Jianhua WANG
;
Lijiao ZHAO
Author Information
1. 北京工业大学生命科学与生物工程学院
- Keywords:
Spinal bifida;
Gene;
Signal pathway;
Phenotype;
Neural tube
- From:
Chinese Journal of Neuromedicine
2019;18(6):622-628
- CountryChina
- Language:Chinese
-
Abstract:
Spinal bifida is one of the phenotypes of neural tube defects,which are influenced by genetic and environmental factors.There are many genes involved in the occurrence of spinal bifida,and the main genes and animal models are mainly concentrated in the signaling pathway.This article reviews the research progresses on pathogenesis of spinal bifida and relationship between key genes,and further clarifies the pathogenesis of spinal bifida,and achieves more effective prevention and control of neural tube defects.
