Recent advance in protective mechanism of regulatory T cells in secondary injury of intracerebral hemorrhage

VernacularTitle:调节性T细胞在脑出血后继发性损伤中的保护机制的研究进展
Author: Huimin ZHU ¹ ; Jixu YU ; Nian WANG ; Lijuan WANG ; Fengyuan CHE
Author Information

1. 山东第一医科大学(山东省医学科学院)研究生部
Keywords: Intracerebral hemorrhage; Secondary injury; Regulatory T cell; Neuroprotection
From: Chinese Journal of Neuromedicine 2019;18(5):501-506
CountryChina
Language:Chinese
Abstract: Intracerebral hemorrhage (ICH) is a serious acute cerebrovascular disease,and secondary injury is one of the important mechanisms of injury after ICH.Studies have confirmed that regulatory T cells (Tregs) play important protective roles after ICH by modulating microglial phenotype and inhibiting inflammation,and other pathways.This article reviews the protective mechanism of Tregs in the secondary injury,in order to provide a new therapeutic target for ICH.