Recent advance in epilepsy associated with autoimmune encephalitis
10.3760/cma.j.issn.1671-8925.2019.02.018
- VernacularTitle:自身免疫性脑炎相关性癫痫的研究进展
- Author:
Xiaoyang CHAI
1
;
Jie WANG
;
Qian PANG
;
Fei HU
;
Keyu YANG
;
Zan DONG
Author Information
1. 山西医科大学研究生院
- Keywords:
Autoimmune encephalitis;
Seizure;
Pathogenesis;
Treatment
- From:
Chinese Journal of Neuromedicine
2019;18(2):207-210
- CountryChina
- Language:Chinese
-
Abstract:
Autoimmune encephalitis (AE) is a novel form of encephalitis associated with antibodies to cell-surface or synaptic proteins. Epileptic seizures act as the predominant manifestation of AE which are triggered by interaction between kinds of antibodies and antigens on cell-surface or intracellular. Patients with AE-related epilepsy are insensitive to antiepileptic drugs but sensitive to immunotherapy. Early initiation of immunotherapy can significantly improve the prognosis. To date, there are few reports on the treatment plan of antiepileptic drug to the patients with AE-related epilepsy. In this review we report the most relevant data about the morbidity, pathogenesis and treatment of AE-related epilepsy with aim of providing better treatment options.
