Recent advance in predictors of conversion of clinical isolated syndrome
10.3760/cma.j.issn.1671-8925.2019.01.020
- VernacularTitle:预测临床孤立综合征转归的相关因子最新研究进展
- Author:
Jintao WANG
1
;
Yan DIN
Author Information
1. 日照市人民医院神经内科 276800
- Keywords:
Clinical isolated syndrome;
Multiple sclerosis;
Predictor;
Conversion
- From:
Chinese Journal of Neuromedicine
2019;18(1):102-106
- CountryChina
- Language:Chinese
-
Abstract:
Clinical isolated syndrome (CIS) is the first episode of neurological symptoms caused by inflammatory demyelinating disease of central nervous system.About 85％ patients with multiple sclerosis (MS) have CIS as onset;about 45％ CIS patients convert to clinically definite MS (CDMS)within two years.Early disease modifying treatment is beneficial to those CIS patients who have high risk of converting to MS,so it is necessary to find predictors to predict CIS converting to MS.In recent years,there are many studies on predictors of CIS converting to MS in CSF,serology,clinical symptoms,and images.We review some recent advances in those studies.
