Recent advance in biomarkers of Alzheimer's disease
10.3760/cma.j.issn.1671-8925.2018.11.019
- VernacularTitle:阿尔茨海默病生物标志物的研究进展
- Author:
Guangying SUN
1
;
Min XUE
Author Information
1. 蚌埠医学院附属淮南市第一人民医院神经内科
- Keywords:
Alzheimer's disease;
Biomarker;
Diagnosis
- From:
Chinese Journal of Neuromedicine
2018;17(11):1172-1176
- CountryChina
- Language:Chinese
-
Abstract:
Alzheimer's disease (AD) is a kind of occult central neurodegenerative disease. The incidence of AD is gradually increased in aged societies. The etiological mechanism of AD is not clear and may be influenced by environmental or genetic factors. At present, clinical diagnosis of AD mainly relies on the measurement of cognitive function scale and the collection of medical history; the main biomarkers used for AD diagnosis are scaffold amyloid protein and Tau protein in the cerebrospinal fluid. In this review, some biomarkers which are helpful for early diagnosis of AD at home and abroad are described.