Recent advance in pathological mechanism and treatments of dysphagia in Parkinson's disease
10.3760/cma.j.issn.1671-8925.2018.10.022
- VernacularTitle:帕金森病吞咽障碍的病理生理机制及治疗进展
- Author:
Li ZHANG
1
;
Liang'e XU
;
Sheng ZHANG
;
Bin XU
;
You WU
Author Information
1. 浙江中医药大学第二临床医学院
- Keywords:
Parkinson's disease;
Dysphagia;
Pathological mechanism;
Treatment
- From:
Chinese Journal of Neuromedicine
2018;17(10):1068-1073
- CountryChina
- Language:Chinese
-
Abstract:
Dysphagia is one of the major non-motor symptoms in Parkinson's disease (PD)patients.The swallowing fimctions in oral,pharyngeal,and esophageal phases are impaired to varied degrees.Dysphagia caused by PD is closely related to the pathophysiological changes of central and peripheral nervous systems.Early clinical symptoms are occult and progressive,which seriously affects the quality of life of PD patients.Although the treatment of dysphagia in PD has progressed to some extent,there is still a lack of effective and reliable treatment methods.Individualized and targeted prevention and treatment programs may help improve patient's quality of life and prognoses.
