Recent advance in telomere and telomerase in study of nervous system diseases
10.3760/cma.j.issn.1671-8925.2018.10.021
- VernacularTitle:端粒与端粒酶在神经系统疾病研究中的新进展
- Author:
Fei WANG
1
;
Chi ZHANG
Author Information
1. 天津医科大学总医院神经内科
- Keywords:
Telomere;
Telomerase;
Cellular senescence;
Nervous system disease
- From:
Chinese Journal of Neuromedicine
2018;17(10):1063-1067
- CountryChina
- Language:Chinese
-
Abstract:
Telomere loss is considered to be one of the important markers of cellular senescence and is closely related to nervous system diseases.Telomerase not only has the function of prolonging telomeres,but also has neuroprotective effect.Telomere and telomerase are expected to be important new targets for the prevention,delay and treatment of nervous system diseases,and will provide new research ideas and treatment strategies for neurological diseases.This paper reviews the recent progress in the study of telomerase and telomerase in nervous system diseases.
