Clinical outcomes of custom-designed polyetheretherketone and titanium in cranioplasty after decompressive craniectomy: a single center study
10.3760/cma.j.issn.1671-8925.2018.08.012
- VernacularTitle:聚醚醚酮与钛网在去骨瓣减压术后颅骨成形术中临床应用效果的单中心回顾性研究
- Author:
Xinlin SUN
1
;
Jihui WANG
;
Min HUANG
;
Fa JIN
;
Qijin HUANG
;
Yiquan KE
Author Information
1. 510282 广州,国家临床重点专科,广东省神经外科临床研究中心,广东省脑功能修复与再生重点实验室,南方医科大学珠江医院神经外科
- Keywords:
Cranioplasty;
Decompressive craniectomy;
Polyetheretherketone;
Titanium;
Complication
- From:
Chinese Journal of Neuromedicine
2018;17(8):825-830
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the clinical outcomes and complications of alloplasfic cranioplasty performed with custom-designed polyetheretherketone (PEEK) and titanium mesh after decompressive craniectomy.Methods Eighty-six patients admitted to our hospital from June 2014 to December 2017 were chosen;and 28 patients underwent cranioplasty with PEEK and 58 with titanium mesh by the same surgical team.The general clinical data and postoperative complications were compared between the two groups.Multivariable Logistic regression analysis was performed to analyze the influencing factors of postoperative complications.The surgical time,molding quality and cost were compared between the two groups.Results Patients in PEEK group trended to be younger and had higher GOS scores as compared with patients in the titanium group,with significant differences (P＜0.05).Overall complication rates of 10.7％ and 32.8％ for PEEK and titanium cranioplasty were identified respectively;as compared with that in titanium group,the incidence of overall complication in PEEK group was significant lower (P＜0.05).Logistic regression analysis identified material was the independent influencing factor for cranioplasty complications (OR=4.486,P=0.047,95％CI:1.021-19.703).Overall satisfaction rate with cranioplasty and aesthetic result in PEEK group was significantly higher than that in titanium group (96.4％ vs.79.3％,P＜0.05);however,the treatment cost for cranioplasty with PEEK was considerably higher than skull bone reconstruction based on titanium mesh.Conclusion Despite of high treatment cost,custom-designed PEEK implants seem to be good choice for patients with large cranial defects after decompressive craniectomy,enjoying few complications and high satisfaction of cranioplasty and aesthetic result.
