Correlation between cerebral micro-bleeds and recurrent stroke after transient ischemic attack
10.3760/cma.j.issn.1671-8925.2018.08.009
- VernacularTitle:脑微出血与短暂性脑缺血发作后脑卒中发生的相关性研究
- Author:
Lin CHANG
1
;
Yueyue CHANG
;
Chuanqing YU
Author Information
1. 淮南东方医院集团总院神经内科
- Keywords:
Cerebral micro-bleed;
Transient ischemic attack;
Stroke;
Risk factor
- From:
Chinese Journal of Neuromedicine
2018;17(8):808-812
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between cerebral micro-bleeds (CMBs) and recurrent stroke after transient ischemic attack (TIA),and to guide early diagnosis of prognoses.Methods A total of 147 patients with TIA,admitted to our hospital from January 2015 to June 2017,were enrolled;29 patients (19.73％) were given anti-platelet therapy,double-antibody treatment was performed in 103 patients (70.07％),15 patients (10.20％) were given anticoagulation,and 108 patients (73.47％) took statins.Intracranial imaging was performed on these patients on admission and one week after different treatments.The general data and biochemical markers were collected;the recurrent stroke after TIA within 90 d was followed up.Univariate analysis and multivariate Logistic regression were used to screen the risk factors for stroke after TIA.Results CMBs were noted in 30 patients (20.41％) at first intracranial imaging;another 2 patients with CMBs were noted at one week after treatments,and there were no significant differences in newly-detected CMBs among different treatment methods (P＞0.05).Nine patients (6.12％) had stroke recurrence.Univariate analysis indicated that the percentages of patients with atrial fibrillation,symptomatic carotid artery stenosis≥ 50％,CMBs and white matter high signal (WMH) and high ABCD2 scores between TIA patients with/without stroke were significantly different (P＜0.05).Multivariate Logistic regression showed that CMBs were the independent risk factors of recurrent stroke after TIA (OR=4.126,P=0.003,95％CI:0.320-2.390).Conclusion CMBs canpredict the risk of stroke recurrence after TIA.
