Risk factors of cerebral microbleeds in patients with cerebrovascular disease
10.3760/cma.j.issn.1671-8925.2018.08.008
- VernacularTitle:脑血管病患者脑微出血的相关危险因素分析
- Author:
Qi QIAO
1
;
Huijuan WANG
;
Zhenzhen QU
;
Zan YUE
;
Binglei WANG
;
Xin BIAN
Author Information
1. 河北医科大学第二医院神经内科
- Keywords:
Cerebral microbleed;
Risk factor;
Cerebrovascular disease
- From:
Chinese Journal of Neuromedicine
2018;17(8):802-807
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the related risk factors of cerebral microbleeds (CMBs) and their relations with leukoaraiosis and lacunar infarction in patients with cerebrovascular disease.Methods One hundred and sixty-four patients with cerebrovascular disease,admitted to our hospital from January 2015 and January 2017 were chosen;susceptibility weighted imaging (SWI) was performed,and the distribution and number of CMBs were recorded by Microbleed Anatomical Rating Scale (MARS).The demographic data,personal history,previous medical history,biochemical indices and imageological examination results of the patients were collected and multivariate Logistic regression analysis was carried out on the basis of these data.Spearman dependence analysis was used to analyze the relations of CMBs with leukoaraiosis and lacunar infarction.Results Age (OR=1.071,P=0.024,95％ CI:1.009-1.137),hypertension (OR=3.875,P=0.012,95％CI:1.347-11.148),leukoaraiosis(OR=2.080,P=0.005,95％ CI:1.245-3.475),lacunar infarction (OR=2.326,P=0.003,95％ CI:1.336-4.050) were independently associated with CMBs.And number of CMBs had positive correlation with severity of leukoaraiosis and number of lacunar cerebral infarcts (r=0.564,P=0.000;r=0.762,P=0.000).Conclusion Age,hypertension,leukoaraiosis,and lacunar infarction are the independent risk factors of CMBs;the severity of CMBs is positively correlated with severity of leukoaraiosis and lacunar infarction.
