Displacement characteristics of intraoperative and postoperative positions of electrodes on CT imaging for subthalamic nucleus-deep brain stimulation in Parkinson's disease
10.3760/cma.j.issn.1671-8925.2018.07.006
- VernacularTitle:帕金森病丘脑底核脑深部电刺激术术中及术后CT影像电极位置偏移特点分析
- Author:
Xusheng HOU
1
;
Fengfei LU
;
Yongyi YE
;
Chen YAO
;
Longping YAO
;
Yang LU
;
Shan XUE
;
Xiaozheng HE
;
Hengxu MAO
;
Xiang SUN
;
Baoyan WANG
;
Chen QIAN
;
Shizhong ZHANG
Author Information
1. 510282 广州,国家临床重点专科,教育部工程技术研究中心,广东省脑功能修复与再生重点实验室,广东省南方医科大学珠江医院神经外科
- Keywords:
Parkinson's disease;
Subthalamic nucleus;
Deep brain stimulation;
Computed tomography image;
Electrode location;
Displacement
- From:
Chinese Journal of Neuromedicine
2018;17(7):678-684
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the displacement characteristics of intraoperative and postoperative positions of electrodes on CT imaging for bilateral subthalamic nucleus-deep brain stimulation (STN-DBS) in Parkinson's disease (PD).Methods A retrospective analysis on preoperative MR imaging,intraoperative and postoperative CT images of 35 patients with PD treated with STN-DBS in our hospital from January 2014 to June 2018 was performed.A three-dimensional coordinate system was established based on preoperative MR imaging.MR imaging/CT fusion technique was used to fuse intraoperative and postoperative CT images with preoperative MR imaging to locate intraoperative and postoperative electrode positions.The displacement characteristics of intraoperative and postoperative electrodes were analyzed.Results The spatial distance between intraoperative and postoperative positions of bilateral electrodes was about 1 mm,and the depth displacement was minimal.The postoperative position of the first side electrode on lateral axis was shifted outwardly from intraopemtive position,and the second side electrode was shifted internally with a small degree;on anterior-posterior axis,the first side electrode obviously shifted backward,and the second side electrode slightly shifted backward.For bilateral electrodes,corresponding coordinate deviation of three axis between intraoperative electrode-preoperative target and postoperative electrode-preoperative target,showed a significant positive linear correlation,therefore,leading out the coordinate deviation regression function model.Conclusions The displacement of electrodes between intraoperative and postoperative positions has obvious rules after STN-DBS in PD,which can guide the adjustment of intraoperative electrode position and predict the postoperative position of electrode.
