Research advances in Alzheimer's disease and DNA methylation
10.3760/cma.j.issn.1671-8925.2018.04.020
- VernacularTitle:阿尔茨海默病和DNA甲基化相关研究进展
- Author:
Qilemuge
1
;
Huriletemuer
;
Chunyu ZHANG
Author Information
1. 内蒙古医科大学研究生院
- Keywords:
Alzheimer's disease;
Epigenetics;
DNA methylation
- From:
Chinese Journal of Neuromedicine
2018;17(4):424-427
- CountryChina
- Language:Chinese
-
Abstract:
Prevalence of Alzheimer's disease,a neurodegenerative disease of the central nervous system,is increasing with the aging of population,causing serious social and family burdens.It is influenced by a variety of factors,including genetic and environmental ones.Epigenetics is an important bridge connecting genetic and environmental factors.DNA methylation,the most important modification in epigenetics,is related to many diseases like aging,cancer and dementia.In this paper,we reviewed the recent studies on the role ofDNA methylation in AD.
