Recent advance in hyperbaric oxygen adjunctive therapy for gliomas
10.3760/cma.j.issn.1671-8925.2018.02.019
- VernacularTitle:高压氧辅助治疗脑胶质瘤的研究进展
- Author:
Yujun XI
1
;
Xiangyu KONG
;
Jiawei MA
;
Yinghao SONG
;
Jun DONG
Author Information
1. 苏州大学附属第二医院神经外科
- Keywords:
Hyperbaric oxygen treatment;
Glioma;
Tumor cell hypoxia;
Radiotherapy;
Chemotherapy
- From:
Chinese Journal of Neuromedicine
2018;17(2):205-208
- CountryChina
- Language:Chinese
-
Abstract:
Hyperbaric oxygen therapy (HBOT) has been widely used in the treatment ofhypoxia,ischemia,and a series of diseases caused by hypoxia and ischemia.The treatment effect of HBOT on gliomas remains controversial.The presence of local hypoxia in gliomas is the main cause of tumor resistance to radiotherapy and chemotherapy;HBOT can improve the oxygen content in these areas,and thus,treatment should be as effective as other hypoxic diseases;however,most researchers believe that in the process of gliomas,the efficacy of HBOT alone is limited,and HBOT is usually not used alone.More commonly,HBOT is commonly used as adjuvant therapy in other treatments (such as radiotherapy and chemotherapy).Based on the above contents,we summarized as follows and put forward the views on the current debate.