Recent advance in atypical clinical manifestations of amyotrophic lateral sclerosis
10.3760/cma.j.issn.1671-8925.2018.01.010
- VernacularTitle:肌萎缩侧索硬化症的非典型临床表现研究进展
- Author:
Huifeng CHEN
1
;
Yuanrong YAO
Author Information
1. 山西医科大学第二医院神经内科
- Keywords:
Amyotrophic lateral sclerosis;
Cognitive impairment;
Extrapyramidal disorder;
Autonomic dysfunction
- From:
Chinese Journal of Neuromedicine
2018;17(1):53-56
- CountryChina
- Language:Chinese
-
Abstract:
Amyotrophic lateral sclerosis (ALS) is a series of upper and lower motor neuron degenerative disorders,characterized by muscle weakness and atrophy,bulbar paralysis and pyramidal signs.Recent studies showed that ALS may present with many atypical clinical manifestations,such as cognitive impairment,autonomic dysfunction,extrapyramidal disorders,paresthesia,and abnormal eye movements.This review summarized the recent understanding of atypical clinical manifestations in ALS.