Influence factors of degrees of Virchow-Robin spaces in acute lacunar stroke patients
10.3760/cma.j.issn.1671-8925.2018.01.005
- VernacularTitle:急性腔隙性脑梗死患者血管周围间隙扩大程度的影响因素研究
- Author:
Fei WANG
1
;
Zhuoxuan YANG
;
Min FEI
;
Yansheng QIAO
Author Information
1. 044000,山西省运城市中心医院神经内科
- Keywords:
Lacunar stroke;
Virchow-Robin space;
Risk factor;
Basal ganglia;
Central semiovale;
Hypertension;
Body mass index
- From:
Chinese Journal of Neuromedicine
2018;17(1):29-33
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the influence factors of degrees of Virchow-Robin Spaces (VRS) in patients with acute first-ever lacunar stroke.Methods Two hundred and thirty-eight patients with first-ever lacunar stroke whose infractions were found in the basal ganglia (n=131) or the central semiovale (n=107) were recruited from our hospital from January 2016 to June 2017.The demographic and clinical characteristics of these patients were collected and magnetic resonance imaging was used to identify the presence and degrees of VRS in the basal ganglia (BG-VRS) and central semiovale (CSO-VRS).Logistic regression models were constructed to identify the influence factors for BG-VRS and CSO-VRS.Results The VRS scores were not statistically different between patients whose infractions were found in basal ganglia and patients whose infractions in central semiovale (P＞0.05).Univariate survival analysis indicated that gender,hypertension percentage,systolic pressure level,and body mass index (BMI) in patients from mild BG-VRS group were significantly different as compared with those in patients from severe BG-VRS group (P＜0.05);hypertension percentage,diabetes mellitus percentage,and BMI in patients from mild CSO-VRS group were significantly different as compared with those in patients from severe CSO-VRS group (P＜0.05).Multivariable Logistic regression analysis showed that hypertension and BMI could significantly influence the severity of BG-VRS (odds ratio [OR] =6.272,95％ confidence interval [CI]:1.931-20.365,P=0.002;OR=0.757,95％CI:0.619-0.927,P=0.007),and BMI could significantly influence the severity of CSO-VRS (OR=0.775,95％CI:0.655-0.918,P=0.004).Conclusion Hypertension is the independent risk factor of degrees of BG-VRS,and BMI is the protective factor of degrees of BG-VRS and CSO-VRS.
