Identification of carotid plaque microcalcification by Micropure imaging
10.3760/cma.j.issn.1671-8925.2017.10.016
- VernacularTitle:Micropure技术检测颈动脉斑块微钙化的初步临床应用
- Author:
Ying HE
1
;
Dan YE
;
Fei HUA
;
Xuegan LIAN
;
Jian WU
;
Ying JIANG
;
Chunxian YUE
;
Song YANG
;
Ning WEI
;
Meng LIU
Author Information
1. 苏州大学附属第三医院超声科
- Keywords:
Carotid;
Microcalcification;
Ultrsound;
Stroke;
Micropure imaging
- From:
Chinese Journal of Neuromedicine
2017;16(10):1056-1059
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between carotid plaque microcalcifcation and ischemic stroke (including transient ischemic attack) and the value of carotid microcalcification in predicting ischemic stroke.Methods Twenty-six patients in accordance with atherothrombosis models classified by Korean modified TOAST classification were enrolled in this study from November 2016 to March 2017.The microcalcification of the bilateral carotid was detected by Micropure imaging and the severity of intracranial ischemic focal lesions was evaluated by Alberta stroke programme early CT scale (ASPECT).The relation of ASPECT scores with microcalcification of the bilateral carotid was analyzed,and the value of carotid microcalcification in predicting ischemic stroke was analyzed by receiver operating characteristic curve method.Results Microcalcifition was detected in 27 of the total 52 carotids (51.92％) in 19 patients,which localized in the fibrous cap in 23 carotids (85.19％) and the basilar part of the plaque in 4 carotids (14.81％).The microcalcification surrounded the macrocalcifiation in 14 carotids (51.85％).The ASPECT scores were 10.85±1.43 in the microcalcifition side,which were significantly higher than those in the side without microcalcifition (11.80±1.19,t=2.584,P=0.013).The area under the curve was 0.673,with sensitivity of 0.667 and specificity of 0.680.Conclusion Micropure imaging maybe a new approach to detect the carotid microcalcification,and plaques with microcalcifition mav easilv cause ipsilateral ischemic stroke.
