Recent advances in combined central and peripheral demyelination
10.3760/cma.j.issn.1671-8925.2017.09.020
- VernacularTitle:中枢和周围神经系统联合脱髓鞘疾病的研究进展
- Author:
Fang WANG
1
;
Yuanrong YAO
Author Information
1. 天津医科大学总医院神经内科
- Keywords:
Combined central and peripheral demyelination;
Anti-neurofascin 155 antibody;
Immune abnormality
- From:
Chinese Journal of Neuromedicine
2017;16(9):966-969
- CountryChina
- Language:Chinese
-
Abstract:
Combined central and peripheral demyelination (CCPD) refers to the demyelmation concurrently or sequentially occuring in the central and peripheral nervous systems.CCPD is a new disease entity,which is different from the independent central or peripheral nervous system demyelination.The pathogenesis of CCPD is unclear.The immune abnormalities may be involved.CCPD has low incidence,various manifestations,no specific biomarkers,and no uniform diagnostic criteria.This review summarizes the etiology,pathogenesis,clinical features,specific biomarkers,imaging characteristics,treatments and prognoses of CCPD to improve our understanding of CCPD.
