Recent advance in hypopituitarism after traumatic brain injury

VernacularTitle:创伤性颅脑损伤后腺垂体功能减退的研究进展
Author: Pengqi WANG ¹ ; Shousen WANG
Author Information

1. 南京军区福州总医院康复医学科
Keywords: Traumatic brain injury; Hypopituitarism; Influencing factor; Pathogenesis
From: Chinese Journal of Neuromedicine 2017;16(9):962-965
CountryChina
Language:Chinese
Abstract: Hypopituitarism after traumatic brain injury (TBI) may result in non-specific neuropsychiatric symptoms,which is commonly occurred in patients suffering from severe traumatic injury,chronic repetitive brain injury,and patients administrated with pain-killer and complicated with subarachnoid hemorrhage,skull base fracture and cerebral hemia.The conceivable pathogenesis of hypopituitarism includes vascular hypothesis,ischemic/anoxia injury,genetic predisposition,autoimmunity and inflammatory response.Detection of basal hormone level or test of hormone stimulation is conducive to the diagnosis of hypopituitarism.Patients with secondary adrenal insufficiency should be given hormone replacement therapy.