Prevalence and risk factors of restless leg syndrome in hemodialysis patients after kidney transplantation failure
10.3760/cma.j.issn.1671-8925.2017.08.015
- VernacularTitle:肾移植失败后血液透析患者不安腿综合征患病率及危险因素调查
- Author:
Houzhen TUO
1
;
Xiaoyang MA
;
Jingjing CHE
;
Zelong TIAN
;
Yinong CUI
;
Kui CHEN
;
Yun XUE
;
Yongbo ZHANG
Author Information
1. 首都医科大学附属北京友谊医院神经内科
- Keywords:
Restless leg syndrome;
Hemodialysis;
Kidney transplantation;
Sleep;
Depression
- From:
Chinese Journal of Neuromedicine
2017;16(8):844-848
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the prevalence and risk factors of restless leg syndrome (RLS) in hemodialysis patients after kidney transplantation failure.Methods Patients of hemodialysis after kidney transplantation failure were investigated by face-to-face interviews,from March to July,2015,at four dialysis units in Beijing.RLS was diagnosed according to the International RLS Study Group (IRLSSG) criteria.The severity of RLS was assessed using International RLS Rating scale.Besides,three validated sleep disorder questionnaires (Hamilton anxiety and depression scale,Epworth sleepiness scale and Pittsburgh sleep quality index) were completed by the patients at the same time.Results Ninety-four hemodialysis patients after kidney transplantation failure were enrolled;46 patients (48.94％) met the diagnosis of RLS,the average age was 53.44±l 1.89 years,and the median time of RLS onset after kidney transplantation failure was 46 months.The International RLS Rating scale scores of the patients were 17.26±7.81;76.0％ patients were above moderate.As compared with the non-RLS patients,patients with RLS used more erythropoietin (44/48 vs.46/46),less ferrila (30/48 vs.19/46),and few hypnotic medicine (10/48 vs.3/46),with significant differences (P＜0.05).The serum ion,serum ferritin and serum Vitamin B12 of patients with RLS were significantly lower as compared with non-RLS patients (P＜0.05);and poorer sleep quality and higher depression scale scores in the patients with RLS were noted as compared with those in the non-RLS patients (P＜0.05).Conclusion The prevalence of RLS in hemodialysis patients after kidney transplantation failure is high,low iron protein content,low serum iron content and low vitamin B12 levels may be risk factors for RLS.
