Diagnosis, treatment and characteristics of adult Moyamoya disease in countryside in the southeast of Hubei province
10.3760/cma.j.issn.1671-8925.2017.07.015
- VernacularTitle:鄂东南基层地区成人烟雾病的发病特点及诊治分析
- Author:
Liang BAI
1
;
Jun LI
;
Feng HE
;
Xiuqing MAO
;
Jun SHI
;
Hansheng YOU
Author Information
1. 435500,湖北省黄梅县人民医院神经内科
- Keywords:
Abnormal basal vascular network disease;
Clinical feature Diagnosis;
Epidemiology
- From:
Chinese Journal of Neuromedicine
2017;16(7):725-729
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical features,diagnosis and treatment of adult Moyamoya disease in countryside of the southeast of Hubei province.Methods Sixty-eight adult patients with Moyamoya disease,selected in countryside of the southeast of Hubei Province from May 2010 to May 2015,were enrolled.The clinical data,including age,gender,address (surrounding of residence),living habit (special hobby),health of family members,past medical history,symptom,confirmation related factors,treatment methods and prognoses,were retrospectively analyzed.Results These patients had high and low incidences in distribution.The ratio of male to female was 1.09:1.The peak age of onset was 35 to 44 years.There were 42 bleeding patients,16 ischemia patients,and 7 patients with atypical symptom,and 3 patients were asymptomatic.Thirty-eight patients (55.9％) had early diagnosis and 30 (44.1％) had late conformed diagnosis;patients with early diagnosis had significantly higher percentages of first diagnosis in the tertiary hospitals,hemorrhagic apoplexy as first onset,high education level and economic level than patients with late conformed diagnosis (P＜0.05).Ten patients died.Eight patients received vascular reconstruction,accounting for 11.8％ (8/58).Conclusions The distributions of adult moyamoya disease are regional cluster.The main age of onset is at the life prime.The initial symptom is hemorrhagic stroke.The time for diagnosis was short in the tertiary hospitals.The ratio of patients receiving vascular reconstruction is low.
