Correlation of wake-up stoke with progressive stroke
10.3760/cma.j.issn.1671-8925.2017.04.014
- VernacularTitle:醒后卒中与进展性卒中的相关性研究
- Author:
Jian WANG
1
;
Mingfeng ZHAI
;
Shugang CAO
;
Tinging GE
;
Jun HE
;
Qian GUO
;
Mingwu XIA
;
Wen'an XU
Author Information
1. 230011,合肥市第二人民医院神经内科
- Keywords:
Wake-up stroke;
Progressive stroke;
Predictive factor
- From:
Chinese Journal of Neuromedicine
2017;16(4):398-401
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the correlation of wake-up stroke with progressive stroke.Methods Three hundred and twelve patients with acute ischemic stroke,admitted to our hospital from January 2014 to December 2015 were divided into progressive stroke group (n=70) and non-progressive stroke group (n=242).Demographic features,clinical characteristics,and incidence of wake-up stroke were compared between the two groups.The association between wake-up stroke and progressive stroke was analyzed.Results The incidence of wake-up stroke,homocysteine level,and fibrinogen level in progressive stroke group were significantly higher than those in the non-progressive stroke group (40.0％ vs.18.2％,P=0.000;[17.486±16.835] μmol/L vs.[14.321±7.251] μmol/L,P=0.023;[3.539±1.009] g/L vs.[3.134±0.775] g/L,P=0.000).Multivariate Logistic regression analysis showed that wake-up stoke,homocysteine and fibrinogen were the independent predictive factors of progressive stroke (OR=2.978,95％CI:1.623-5.464,P=0.000;OR=1.026,95％CI:1.002-1.052,P=0.035;OR=1.800,95％CI:1.310-2.472,P=0.000).Conclusion Wake-up stoke is a predictive factor of progressive stroke.
