Effect of Subcapsular Orchiectomy on Serum Testosterone in Rats.
- Author:
Jun Kyu SUH
1
;
Tong Choon PARK
Author Information
1. Department of Urology, College of Medicine, Yeungnam University, Taggu, Korea.
- Publication Type:Original Article
- Keywords:
subcapsular orchiectomy;
testosterone
- MeSH:
Animals;
Humans;
Models, Animal;
Orchiectomy*;
Rats*;
Testosterone*
- From:Korean Journal of Urology
1986;27(1):45-48
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The subcapsular orchiectomy is far more acceptable than a total orchiectomy to patients with prostatic carcinoma. To data, however, it has not been widely used clinically, because its effectiveness in reducing serum androgen levels has remained controversial. We designed this study, to determine if a subcapsular orchiectomy might be as effective as the total orchiectomy in lowering serum testosterone levels, with a controlled rat model. The results support that the subcapsular orchiectomy is as hormonally complete as a total orchiectomy in lowering serum testosterone, and provide us with a basic guideline to be applied to clinical management for prostatic carcinoma.
