Efficacy of SolitaireTM stent arterial embolectomy in treating acute cardiogenic cerebral embolism
10.3760/cma.j.issn.1671-8925.2017.01.003
- VernacularTitle:Solitaire支架动脉取栓术治疗急性心源性脑栓塞疗效观察
- Author:
Maolin FU
1
,
2
;
Xueling XIAO
;
Shuanghu WANG
;
Qiuxiang LU
;
Wenqin HE
;
Huifang XIE
Author Information
1. 510280广州,南方医科大学珠江医院神经内科
2. 362000泉州,南方医科大学附属解放军第一八○医院神经内科
- Keywords:
Cardiogenic cerebral embolism;
Arterial embolectomy;
Clinical prognosis;
Safety;
Posterior circulation
- From:
Chinese Journal of Neuromedicine
2017;16(1):11-16
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the efficacy and safety of Solitaire stent arterial embolectomy in the treatment of acute cardiogenic cerebral embolism.Methods The data of 24 patients who underwent Solitaire stent arterial embolectomy,either alone or in combination with reorganization type tissue plasminogen activator (rt-PA) intravenous thrombolysis,to treat acute cardiogenic cerebral embolism in our hospital were collected.These results between October 2012 and March 2016 were compared with 21 control patients who were treated using only rtPA Ⅳ thrombolysis.The short-term efficacy,long-term clinical outcomes,complications,and mortality rate of these two groups were compared,and the clinical outcomes of these patients with posterior circulation infarction in the two groups were further assessed.Results The time between onset and rt-PA administration in the study group (median time:3.17 h) was significantly shorter than that in the control group (4.00 h,P＜0.05);rt-PA dose used in both two groups was 50 mg.NIHSS scores and Glasgow Coma scale scores at discharge,and modified Rankin scale (mRs) scores 3 and 6 months after treatment in the study group were significantly higher than those in the control group (P＜0.05).There were no significant differences in symptomatic intra-cerebral hemorrhage,high perfusion encephalopathy,incidence of hernia,or mortality between the two groups (P＞0.05).The mRS scores 3 months after treatment in patients with posterior circulation infarction (2) were significantly lower than those in the control group (3,P＜0.05).Conclusions As compared with simple venous thrombolytic therapy,Solitaire stent embolectomy can significantly improve short-term neurological function and long-term prognosis in patients with acute cardiogenic cerebral embolism,enhance their life quality,without increasing the complication incidence and mortality rate.It is safe and effective,and patients with posterior circulation infarction can also be treated by arterial embolectomy.
