Recent advance in clinical research of low-frequency deep brain stimulation of pedunculopontine nucleus in Parkinson's disease
10.3760/cma.j.issn.1671-8925.2016.11.022
- VernacularTitle:脚桥核低频深部脑刺激治疗帕金森病的研究进展
- Author:
Junbin CAI
1
;
Wangming ZHANG
Author Information
1. 510282广州,国家临床重点专科,教育部工程技术研究中心,广东省脑功能修复与再生重点实验室,南方医科大学珠江医院神经外科
- Keywords:
Parkinson's disease;
Pedunculopontine nucleus;
Deep brain stimulation
- From:
Chinese Journal of Neuromedicine
2016;15(11):1185-1188
- CountryChina
- Language:Chinese
-
Abstract:
Deep brain stimulation (DBS) has been widely used in the treatment of a variety of functional neurological diseases.The high-frequency electrical stimulation of subthalamic nucleus can improve tremor,bradykinesia,and rigidity of patients with Parkinson's disease,however,the effects of DBS on gait and balance disorders don't get very good improvement.Recently,clinical studies have found that low frequency pedunculopontine nucleus stimulation can relieve these axial symptoms.Hence we will summarize the clinical researches on the low-frequency deep brain stimulation of pedunculopontine nucleus.