Risk factors of hemorrhage of cerebral arteriovenous malformations in children and treatment strategies of these patients by endovascular embolization
10.3760/cma.j.issn.1671-8925.2016.11.010
- VernacularTitle:儿童颅内动静脉畸形破裂出血的危险因素分析及血管内栓塞治疗体会
- Author:
Jian YIN
1
;
Lingfeng LAI
;
Xin ZHANG
;
Ran LI
;
Xifeng LI
;
Xuying HE
;
Chuanzhi DUAN
Author Information
1. 浙江省中西医结合医院神经外科
- Keywords:
Intracranial arteriovenous malformation;
Children;
Endovascular embolization
- From:
Chinese Journal of Neuromedicine
2016;15(11):1136-1141
- CountryChina
- Language:Chinese
-
Abstract:
Objective To indentify the risk factors of hemorrhage of cerebral arteriovenous malformations (AVMs) in children,and further conclude the treatment strategies and safety of these patients by endovascular embolization.Methods The clinical data of 56 patients with AVMs aged 3-14 years,admitted to our hospital from June 2005 to June 2015,were retrospectively analyzed.The risk factors of hemorrhage of these patients were identified by univariate and multivariate analyses;and the treatment strategies by endovascular embolization were analyzed.Results Univariate analysis indicated that small size of malformation vascular mass was the independent risk factor of hemorrhage for patients with AVMs in children (OR=0.292,95％CI:0.106-0.805,P=0.017).For 56 patients treated by endovascular embolization,a total of 121 feeding pedicles were embolized,and the mean obliteration rate of AVMs was 79％ (20％-100％).Finally,only 9 patients (7.9％) suffered embolization-related complications,such as headache,facial paralysical,hemianopsia,and activity obstacle;however,no patients suffered severe disability or death.After a follow-up of 2 months to 36 months (mean=17 months),all childem had favorable outcome,and none suffered intracerebral hemorrhage or recurrent AVMs.Conclusions Small size of malformation vascular mass is the independent risk factor of hemorrhage of patients with AVMs in children.The endovascular embolization of patients with intracranial AVM in children is efficacy and safe with few complications.
