Comparative analysis of clinical manifestations of syphilis cerebrovascular infarction and atherosclerotic cerebrovascular infarction
10.3760/cma.j.issn.1671-8925.2016.07.004
- VernacularTitle:梅毒性脑动脉炎性脑梗死与动脉粥样硬化性脑梗死的临床对比分析
- Author:
Xiaoyun FENG
1
;
Xuean MO
;
Huahong QIN
Author Information
1. 武警广西总队医院神经内科
- Keywords:
Neurosyphilis;
Atherosclerosis;
Cerebral infarction;
DSA
- From:
Chinese Journal of Neuromedicine
2016;15(7):664-668
- CountryChina
- Language:Chinese
-
Abstract:
Objective To search the clinical methods for identification of syphilis cerebrovascular infarction from atherosclerotic cerebrovascular infarction. Methods The clinical manifestations, laboratory examination results, MRI results and DSA characteristics of 20 patients with cerebrovascular infarction (syphilis group) and 80 patients with atherosclerotic cerebrovascular infarction (atherosclerosis group), admitted to our hospital from February 2008 to August 2014, were retrospectively analyzed and compared. Results As compared with patients of the atherosclerosis group, the patients of syphilis group had significantly younger onset age ([47.4±11.3] y vs. [62.7±11.0]y), higher male proportion (9:1 vs. 4:1), higher proportion of farmers and individual workers (70%vs. 21.2%, P<0.05). Dizziness (35%) and headache (20%) were more common as the first symptom, and memory loss (15%) and walking instability (15%) were more common as first symptoms in patients of syphilis group, while limb weakness (75%) and unclear speech (35%) were more common as first symptoms in patients of atherosclerosis group; significant differences were noted between the two groups (P<0.05). In MRI, lesions in lobes of the brain (45.0%) were more common in syphilis group, and lesions in the basal ganglia were (67.5%)more common in atherosclerosis group; significant difference was noted between the two groups (P<0.05);lesions involved more than two sites (38.8%) or even three sites lesions (45.0%) were more common in patients of syphilis group. In DSA, middle cerebral artery stenosis (65%), internal carotid artery stenosis (38.8%) were more frequently found in patients of syphilis group, and more than two (75.0%) or even three (55.0%) vascular involvements were more common in syphilis group;significant difference was noted between the two groups (P<0.05). Conclusion The clinical features and imaging features of the syphilis cerebrovascular infarction are different from atherosclerotic cerebrovascular infarction; DSA is important in the diagnosis and treatment of syphilis cerebrovascular infarction.
