Lingo-1 as a new therapeutic target for central nervous system injury
10.3760/cma.j.issn.1671-8925.2016.04.021
- VernacularTitle:Lingo-1在中枢神经系统损伤疾病中的应用
- Author:
Lei SUO
1
;
Yinxiang YANG
;
Wenyan TANG
;
Zuo LUAN
Author Information
1. 解放军海军总医院儿科
- Keywords:
Lingo-1;
Central nervous system injury;
Neuronal inhibitory factor
- From:
Chinese Journal of Neuromedicine
2016;15(4):421-424
- CountryChina
- Language:Chinese
-
Abstract:
Lingo-1 as a dark horse is a potent negative regulator of neuron and oligodendrocyte survival,neurite extension,axon regeneration,oligodendrocyte differentiation,axonal myelination and functional recovery in central nervous system injury.The structure,distribution and biological characteristics of Lingo-1 and its role in the central nervous system injury are collected and analyzed;the role and status of Lingo-1 in the field of nerve regeneration are further clarified.The further research of Lingo-1 will broaden the treatment method and target of new drugs in the field of nerve regeneration
