Metabonomics in study of Parkinson's disease biomarkers
10.3760/cma.j.issn.1671-8925.2016.04.020
- VernacularTitle:代谢组学在帕金森病生物标记研究中的应用
- Author:
Yan WANG
1
;
Zhongxin ZHAO
Author Information
1. 解放军第八十八医院神经内科
- Keywords:
Parkinson's disease;
Metabonomics;
Biomarker
- From:
Chinese Journal of Neuromedicine
2016;15(4):418-420
- CountryChina
- Language:Chinese
-
Abstract:
Parkinson's disease (PD) is a common neurological degenerative diseases.Neuron degeneration process is irreversible;therefore,the correct diagnosis is critical and reliable biomarkers are urgently needed.With the development of molecular biology,some nonspecific biomarker detection methods,such as metabolomics,have been used in the study ofPD.Metabonomics provides a technology and a new technical platform for testing comprehensive metabolites of PD.Metabonomics is very important for biomarker screening in PD.In this paper,the concept,research methods and research progress of metabonomics in PD are reviewed.