Microembolic signal monitoring by trans-cranial Doppler in patients with carotid artery stenosis and its intervention therapy
10.3760/cma.j.issn.1671-8925.2016.03.014
- VernacularTitle:颈动脉狭窄患者微栓子的监测及治疗
- Author:
Zhenhu QIAO
1
;
Weidong NONG
;
Yanping FAN
;
Heping YANG
;
Yang CHEN
;
Yinghai WEI
Author Information
1. 广西壮族自治区民族医院神经内科
- Keywords:
Intracranial carotid stenosis;
Transcranial Doppler;
Microembolic signal
- From:
Chinese Journal of Neuromedicine
2016;15(3):289-291
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the microembolic signal (MES) in patients with carotid artery stenosis by transracial Doppler (TCD) diasonograph,and explore the influence of intervention treatment in MES of patients with carotid artery stenosis.Methods One hundred and fifty-eight patients with carotid artery stenosis,admitted to our hospital from March 2009 to November 2014,were enrolled as carotid artery stenosis group;and 158 workers from our hospital without carotid artery stenosis were used as control group.TCD was used to monitor the MES at the initiative internal carotid artery in the two groups;and then,10 d after aspirin enteric coated tablets (100 mg/d) on platelet aggregation and torvastatin (20 mg/d) treatment,MES was monitored again;the MES positive rate between the two groups or in carotid artery stenosis group between before and after medication was compared.Results As compared with the control group (1.9％),the carotid artery stenosis group (36.1％) had significantly increased MES positive rate (P＜0.05).In the carotid artery stenosis group,MES positive rate before treatment (36.1％) was significantly higher than that after treatment (7.6％,P＜0.05).Conclusion MES positive rate in the cerebral blood flow in patients with carotid artery stenosis is increased;treatment by drugs can reduce the microemboli positive rate.
