Low frequency ultrasound in treatment of middle cerebral artery atherosclerosis acute ischemic stroke: a clinical observation study
10.3760/cma.j.issn.1671-8925.2016.01.004
- VernacularTitle:低频超声治疗对动脉粥样硬化性大脑中动脉狭窄急性脑梗死患者的临床疗效观察
- Author:
Xiafeng YANG
1
;
Fengyun WANG
;
Yanhui LI
;
Guifang WANG
;
Jingru WANG
;
Chunxia WU
;
Xiaoqian YANG
Author Information
1. 252000,聊城市脑科医院神经内科
- Keywords:
Middle cerebral artery;
Atherosclerosis;
Low frequency ultrasound;
High-sensitivity C-reactive protein
- From:
Chinese Journal of Neuromedicine
2016;15(1):15-19
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical effect of low frequency ultrasound on middle cerebral artery (MCA) atherosclerosis acute ischemic stroke.Methods One hundred patients with symptomatic atherosclerotic MCA atherosclerosis acute ischemic stroke were randomly divided into low frequency ultrasound group (n=50) and control group (n=50).The patients of the control group were administered routine medicine,while the patients of the low frequency ultrasound group accepted low frequency ultrasound besides routine medicine.The main observation indexes included National Institutes of Health Stroke Scale (NIHSS) scores,peak systolic velocity of the MCA stenosis segment,microemboli signal and serum high-sensitivity C-reactive protein (hs-CRP) concentrations before and after the treatment.Results Fourteen days after treatment,the NIHSS scores of the low frequency ultrasound group (3.70±4.88) were significantly lower than those in the group (4.68±5.49,P＜0.05);the peak systolic velocity of the MCA stenosis segment in the low frequency ultrasound group after treatment was (158.60±34.33) cm/s,which was significantly lower than that before treatment,namely (189.94± 28.21) cm/s (P＜0.05);7 and 14 days after treatment,the microemboli positive rate of the low frequency ultrasound group (17.00％ and 6.00％) was significantly lower than that in the control group (67.00％ and 8.30％,P＜0.05);serum hs-CRP concentration of the low frequency ultrasound group and control group after treatment was significantly lower than that before treatment (P＜0.05),and that in the low frequency ultrasound group was significantly lower than that in the control group (P＜0.05).Conclusion Low frequency ultrasound assisted therapy can lower serum hs-CRP level,improve hemodynamic MCA stenosis segment,inhibit MCA stenosis segment origin microemboli,and promote neurological recovery in patients with MCA stenosis.
